Researchers have recently published pilot clinical trial data from a five-day Fasting Mimicking Diet (FMD) that was connected with autophagy, which is the increased activity of the body’s natural cellular clean-up process.1 Additionally, there were improvements seen in key metabolic health indicators. Scientists from Cedars-Sinai Medical Center (Los Angeles, California) and UT Health San Antonio … Read more

Sundry Photography/Getty Images You may enter Costco with an empty cart one moment — as many do — and exit it the next, cart filled to the brim with things you can’t even remember putting there. You’ll suddenly have new Tupperware, a gigantic bag of oranges, maybe … Read more

It may come as a surprise, but bacteria love to grow inside tumors. It’s the environment—tumors are typically acidic, have low amounts of oxygen, and are filled with dead cells, which all facilitate bacterial growth. Perhaps more importantly, the immune system can’t easily find and destroy microbes in the tumor core, giving bacteria a safe … Read more

Published December 20, 2025 03:00AM I didn’t even like the pie. It was too sweet and store-bought. Still, there I was—standing barefoot in the kitchen, fork in hand, jeans already unbuttoned, eating it straight from the plastic container. I wasn’t hungry, but I was still eating. The holiday kitchen is its own ecosystem—spices in the … Read more

If you’re looking to refresh your interiors in 2026, Crown Paints wants to help you make it happen. The brand is kickstarting the New Year with a very exciting giveaway, where one lucky winner will receive £250 worth of its top quality paints to help breathe new life into their space. If you win, you’ll … Read more

Welcome to the weekend, my friends! Can you believe we’re just a few days away from Christmas?? As I started writing this today, I realized this will be the 500th Little Things newsletter! This was never really something I planned to do. I just really enjoy sharing our life with you in this way and … Read more

Hypoxia, a lack of oxygen, is associated with numerous diseases including cancer, heart disease, arthritis, and diabetes. Certain tumors grow very rapidly in hypoxic environments and the ability to identify such tumors could be extremely useful for determining the best course of treatment. Using non-invasive magnetic resonance imaging (MRI) would be an ideal way to … Read more

This is the mushroom lasagna I make when no-one is looking. The one where I cut a couple of traditional corners, add a few personal touches and, quite honestly, never look back. Sometimes I go long-form and use homemade pasta for the layers, other times it’s all about keeping the process quick — store-bought lasagna … Read more

On a windy Tuesday night, there wasn’t an empty spot in the 80-seat, dimly lit dining room. INDN is the brainchild of husband-and-wife dream team, Sim Bakshi and Kanika Vij, who saw a gap in Manhattan’s dining scene and knew exactly how they wanted to fill it. The result is a vibrant playground where cocktails … Read more

Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA ‘instructions’ into target cells, providing them with a blueprint to make specific proteins. These proteins could help tissues to regenerate, replace misfunctioning proteins, or prompt an immune response, providing a variety … Read more